BIOLOGY BASICS: HOW TESTOSTERONE WORKS
Testosterone! The king of masculinity. Without it, you are destined for a life of
obesity, low energy, and wimpy girlie arms (if you like wimpy girlie arms, this
article is not for you). Without further
ado (I like classic clichés), lets jump into it (I can’t help myself).
WHAT IS TESTOSTERONE?
Testosterone is a sex hormone and an anabolic steroid. As I’ve mentioned before, hormones are
chemical messengers in the body. Testosterone is responsible for the maintenance and regulation of the
reproductive system. It controls the
process by which the body makes sperm, and develops secondary sex characteristics
(bone mass, muscle mass, body hair, thickening of the vocal cords, penis and
prostate development, etc.). It also
helps maintain youthful energy levels, and faster recovery. Men and women both have testosterone, however
men make more (well most men).
WHAT MAKES YOUR BODY
I’m glad you asked. And if you didn’t, you are about to learn something. Your body’s testosterone production is based
upon several feedback loops. What’s a
feedback loop you ask? A hormonal
feedback loop is your body’s way of controlling the release of hormones from
the different endocrine organs in your body (pituitary gland, testes, ovaries,
etc.). It works like a water damn. If there is too much water downstream, the
damn operators stop the flow of water. If there is too little water downstream, the damn operators open up the
flow of water.
THE HYPOTHALAMIC-PITUITARY-GONADAL (HPG) AXIS
The HPG Axis is your
body’s testosterone feedback loop. When
your brain senses that you need more testosterone downstream, the hypothalamus
releases Gonadotropin Releasing Hormone (GnRH) into the blood stream. Your pituitary gland then receives the GnRH,
and releases Luteinizing Hormone (LH) and Follicle Stimulating Hormone
(FSH). LH then travels to the Leydig
cells, located in the testes, and tells them to produce testosterone. FSH travels to the Sertoli cells and tells
them to start the process of making sperm. Most natural testosterone boosters contain ingredients that make your
body produce more LH and FSH, such as N-Methyl-D-aspartic acid and Tribulus
Terrestris. Now you know how they
work! If you want a potent natural test
booster, I would recommend ALPHA PCT (click
HOW IS TESTOSTERONE
The Leydig cells make testosterone from cholesterol. Cholesterol binds with the enzyme Cytochrome
P450 and is converted into pregnenolone. Pregnenolone is then converted into androstenedione, progestogens,
estrogens, glucocorticoids, mineralocorticoids, DHEA, Testosterone, and other
androgens. It should also be noted that DHEA can also be
converted into testosterone. However,
most of your DHEA is made by the Adrenal Glands.
WHAT HAPPENS NEXT?
Once testosterone is released into the blood stream, most of
it binds with Sex Hormone Binding Globulin (SHBG) or Albumin. Albumin-Bound testosterone has a weaker bond
than SHBG-Bound testosterone. However,
both are unusable by the body. The small
percentage that doesn’t get bound is called Free Testosterone.
TESTOSTERONE AND MUSCLE
Free testosterone is the only testosterone that can be used
by our bodies. Free testosterone then
binds with the targeted Androgen Receptor (AR), located on the outside of the
cell. The Free testosterone then enters
the cell and binds with the Androgen Receptor Protein (ARP). The ARP then enters the nucleus of the cell
and activates specific genes. If it is a
muscle cell, then the nucleus signals the beginning of protein synthesis. Protein synthesis is the process of turning
amino acids into new muscle tissue.
If you have been able to keep up so far, you may now see the
connection between DHEA and Testosterone. Now you know why several companies have started making DHEA products. In fact, Chaos and Pain makes Chemical One
(1-DHEA) and Chemical Four (4-DHEA). Testosterone binds with the Androgen Receptors (ARs) on muscle cells. For more info on Chemical One and Chemical
WRAPPING IT ALL UP
So, as you can see, the process by which your body makes
testosterone is complex (to say the least). However, now you know how and why some of the best natural testosterone
boosters and DHEA products work. The
bottom line (like I said before, I like classic clichés) is that testosterone
is the king of big muscles, ripped abs, and being manly!
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